FREE ELECTRONIC LIBRARY - Dissertations, online materials

Pages:     | 1 |   ...   | 8 | 9 || 11 | 12 |   ...   | 16 |


-- [ Page 10 ] --

181. Chen,Y., Kramer,D.L., Jell,J., Vujcic,S., and Porter,C.W. (2003) Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase. Mol.Pharmacol., 64, 1153Kuhnle,G., Spencer,J.P., Chowrimootoo,G., Schroeter,H., Debnam,E.S., Srai,S.K., Rice-Evans,C., and Hahn,U. (2000) Resveratrol is absorbed in the small intestine as resveratrol glucuronide.

Biochem.Biophys.Res.Commun., 272, 212-217.

183. Andlauer,W., Kolb,J., Siebert,K., and Furst,P. (2000) Assessment of resveratrol bioavailability in the perfused small intestine of the rat. Drugs Exp.Clin.Res., 26, 47-55.

184. Asensi,M., Medina,I., Ortega,A., Carretero,J., Bano,M.C., Obrador,E., and Estrela,J.M. (2002) Inhibition of cancer growth by resveratrol is related to its low bioavailability. Free Radic.Biol.Med., 33, 387-398.

185. Bertelli,A., Bertelli,A.A., Gozzini,A., and Giovannini,L. (1998) Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp.Clin.Res., 24, 133-138.

186. Marier,J.F., Vachon,P., Gritsas,A., Zhang,J., Moreau,J.P., and

Ducharme,M.P. (2002) Metabolism and disposition of resveratrol in rats:

extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model. J.Pharmacol.Exp.Ther., 302, 369-373.

187. Soleas,G.J., Angelini,M., Grass,L., Diamandis,E.P., and Goldberg,D.M.

(2001) Absorption of trans-resveratrol in rats. Methods Enzymol., 335, 145-154.

188. Vitrac,X., Desmouliere,A., Brouillaud,B., Krisa,S., Deffieux,G., Barthe,N., Rosenbaum,J., and Merillon,J.M. (2003) Distribution of [14C]-transresveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration. Life Sci., 72, 2219-2233.

–  –  –

189. Kaldas,M.I., Walle,U.K., and Walle,T. (2003) Resveratrol transport and metabolism by human intestinal Caco-2 cells. J.Pharm.Pharmacol., 55, 307-312.

190. Lancon,A., Delma,D., Osman,H., Thenot,J.P., Jannin,B., and Latruffe,N.

(2004) Human hepatic cell uptake of resveratrol: involvement of both passive diffusion and carrier-mediated process.

Biochem.Biophys.Res.Commun., 316, 1132-1137.

191. Goldberg,D.M., Yan,J., and Soleas,G.J. (2003) Absorption of three winerelated polyphenols in three different matrices by healthy subjects.

Clin.Biochem., 36, 79-87.

192. Walle,T., Hsieh,F., DeLegge,M.H., Oatis,J.E., Jr., and Walle,U.K. (2004) High absorption but very low bioavailability of oral resveratrol in humans.

Drug Metab Dispos., 32, 1377-1382.

193. Wenzel,E., Soldo,T., Erbersdobler,H., and Somoza,V. (2005) Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats.

Mol.Nutr.Food Res., 49, 482-494.

194. Bertelli,A.A., Giovannini,L., Stradi,R., Urien,S., Tillement,J.P., and Bertelli,A. (1996) Kinetics of trans- and cis-resveratrol (3,4',5trihydroxystilbene) after red wine oral administration in rats.

Int.J.Clin.Pharmacol.Res., 16, 77-81.

195. Vitaglione,P., Sforza,S., Galaverna,G., Ghidini,C., Caporaso,N., Vescovi,P.P., Fogliano,V., and Marchelli,R. (2005) Bioavailability of trans-resveratrol from red wine in humans. Mol.Nutr.Food Res., 49, 495Karlsson,P.C., Huss,U., Jenner,A., Halliwell,B., Bohlin,L., and Rafter,J.J.

(2005) Human fecal water inhibits COX-2 in colonic HT-29 cells: role of phenolic compounds. J.Nutr., 135, 2343-2349.

197. Rafter,J.J., Child,P., Anderson,A.M., Alder,R., Eng,V., and Bruce,W.R.

(1987) Cellular toxicity of fecal water depends on diet. Am.J.Clin.Nutr., 45, 559-563.

198. Allinger,U.G., Johansson,G.K., Gustafsson,J.A., and Rafter,J.J. (1989) Shift from a mixed to a lactovegetarian diet: influence on acidic lipids in fecal water--a potential risk factor for colon cancer. Am.J.Clin.Nutr., 50, 992-996.

199. Liao,Q., Yang,W., Jia,Y., Chen,X., Gao,Q., and Bi,K. (2005) LC-MS determination and pharmacokinetic studies of ursolic acid in rat plasma after administration of the traditional chinese medicinal preparation LuYing extract. Yakugaku Zasshi, 125, 509-515.

200. Andersson,D., Cheng,Y., and Duan,R.D. (2007) Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin

–  –  –

201. Gescher,A.J. and Steward,W.P. (2003) Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: a conundrum. Cancer Epidemiol.Biomarkers Prev., 12, 953Pervaiz,S. (2003) Resveratrol: from grapevines to mammalian biology.

FASEB J., 17, 1975-1985.

203. Cleophas,T.J. (1999) Wine, beer and spirits and the risk of myocardial infarction: a systematic review. Biomed.Pharmacother., 53, 417-423.

204. Reuben,A. (2007) Alcohol and the liver. Curr.Opin.Gastroenterol., 23, 283-291.

205. Mertens-Talcott,S.U. and Percival,S.S. (2005) Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells. Cancer Lett., 218, 141-151.

206. Chan,M.M., Mattiacci,J.A., Hwang,H.S., Shah,A., and Fong,D. (2000) Synergy between ethanol and grape polyphenols, quercetin, and resveratrol, in the inhibition of the inducible nitric oxide synthase pathway. Biochem.Pharmacol., 60, 1539-1548.

207. Fang,J.G., Lu,M., Chen,Z.H., Zhu,H.H., Li,Y., Yang,L., Wu,L.M., and Liu,Z.L. (2002) Antioxidant effects of resveratrol and its analogues against the free-radical-induced peroxidation of linoleic acid in micelles.

Chemistry., 8, 4191-4198.

208. Bhat,K.P., Lantvit,D., Christov,K., Mehta,R.G., Moon,R.C., and Pezzuto,J.M. (2001) Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer Res., 61, 7456-7463.

209. Tessitore,L., Davit,A., Sarotto,I., and Caderni,G. (2000) Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression. Carcinogenesis, 21, 1619-1622.

210. Banerjee,S., Bueso-Ramos,C., and Aggarwal,B.B. (2002) Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9. Cancer Res., 62, 4945-4954.

211. Li,Z.G., Hong,T., Shimada,Y., Komoto,I., Kawabe,A., Ding,Y., Kaganoi,J., Hashimoto,Y., and Imamura,M. (2002) Suppression of Nnitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by resveratrol. Carcinogenesis, 23, 1531-1536.

–  –  –

defense-related gene expression in an animal model of human familial adenomatous polyposis. Nutr.Cancer, 39, 102-107.

213. Dorai,T. and Aggarwal,B.B. (2004) Role of chemopreventive agents in cancer therapy. Cancer Lett., 215, 129-140.

214. Yu,L., Wu,S.L., Zhang,M., and Pan,C.E. (2003) [Effect of resveratrol alone and its combination with cyclosporin A on the immune function of human peripheral blood T lymphocytes]. Xi.Bao.Yu Fen.Zi.Mian.Yi.Xue.Za Zhi., 19, 549-551.

215. Kubota,T., Uemura,Y., Kobayashi,M., and Taguchi,H. (2003) Combined effects of resveratrol and paclitaxel on lung cancer cells. Anticancer Res., 23, 4039-4046.

216. Sun,Z.J., Pan,C.E., Liu,H.S., and Wang,G.J. (2002) Anti-hepatoma activity of resveratrol in vitro. World J.Gastroenterol., 8, 79-81.

217. Wu,S.L., Sun,Z.J., Yu,L., Meng,K.W., Qin,X.L., and Pan,C.E. (2004) Effect of resveratrol and in combination with 5-FU on murine liver cancer.

World J.Gastroenterol., 10, 3048-3052.

218. Rezk,Y.A., Balulad,S.S., Keller,R.S., and Bennett,J.A. (2006) Use of

resveratrol to improve the effectiveness of cisplatin and doxorubicin:

study in human gynecologic cancer cell lines and in rodent heart.

Am.J.Obstet.Gynecol., 194, e23-e26.

219. Shankar,S., Siddiqui,I., and Srivastava,R.K. (2007) Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells. Mol.Cell Biochem..

220. Fulda,S. and Debatin,K.M. (2004) Sensitization for tumor necrosis factorrelated apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res., 64, 337-346.

221. Sale,S., Verschoyle,R.D., Boocock,D., Jones,D.J., Wilsher,N., Ruparelia,K.C., Potter,G.A., Farmer,P.B., Steward,W.P., and Gescher,A.J. (2004) Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene. Br.J.Cancer, 90, 736-744.

222. Roberti,M., Pizzirani,D., Simoni,D., Rondanin,R., Baruchello,R., Bonora,C., Buscemi,F., Grimaudo,S., and Tolomeo,M. (2003) Synthesis and biological evaluation of resveratrol and analogues as apoptosisinducing agents. J.Med.Chem., 46, 3546-3554.

–  –  –

B., STEIN, J. (2005) Activation of PPARγ is not involved in butyrateinduced epithelial cell differentiation. Exp Cell Res 310(1): 196-204.

2. ULRICH, S., LOITSCH, S., RAU O., VON KNETHEN, A., BRÜNE, B., SCHUBERTZSILAVECZ, M., STEIN, J. (2006) Peroxisome-Proliferator activated receptor γ as a molecular target of resveratrol-induced modulation of polyamine metabolism. Cancer Res 66(14): 7348-54.


(2006) PPARγ is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2. Apoptosis 11(10): 1801-11.

4. ULRICH, S., HUWILER, A., LOITSCH, S., SCHMIDT, H., STEIN J. (2007) De novo ceramide biosynthesis is assaociated with resveratrol-induced

inhibition of ornithine decarboxylase activity. Biochem Pharmacol 74(2):


5. ULRICH, S., JUNG, B., LOITSCH, S., KAMPAN, W., STEIN, J. (2007) Ursolic acid induces apoptosis through PPARγ mediated SSAT-activation in colon cancer cells (submitted)


1. WOLTER, F., ULRICH, S., STEIN, J. (2004) Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines. J Nutr 134(12): 3219-22. Review

–  –  –

2. ULRICH, S., WOLTER, F., STEIN, J. (2005) Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in carcinogenesis.

Mol Nutr Food Res 49(5): 452-61. Review VORTRÄGE I. Ulrich, S., Loitsch, S., Huwiler, A., Rau, O., Stein, J. “Resveratrol modulates polyamine metabolism of colorectal cancer cells via two different signal transduction pathways”, anlässlich der 2nd International Conference on Polyphenols and Health, Davis, CA, October 4-7, 2005 II. Ulrich, S., Jung, B., Buettner, S., Stein, J (2006) “Molecular characterization of the chemopreventive activity of pentacyclic triterpene ursolic acid”, anlässlich der Digestive Disease Week, Los Angeles, CA, May 20-25, 2006 III. Ulrich, S., Huwiler, A., Loitsch, S., Schmidt, H., Stein, J. (2006) „De novo ceramide biosynthesis is involved in resveratrol-induced inhibition of ornithine decarboxylase activity”, anlässlich der 3rd International Conference on Polyphenols Applications in Nutrition and Health, Malta, October 26-27, 2006 IV. Ulrich, S., Büttner, S., Stein, J. (2007) “Molecular characterization of the anti-angiogenic properties of the pentacyclic triterpene ursolic acid, anlässlich der Digestive Disease Week, Washington, DC, May 19-24, V. Ulrich, S., Kampan, W., Stein, J. (2007) “Resveratrol sensitizes colorectal cancer cells to oxaliplatin-induced cell growth inhibition”, anlässlich der Digestive Disease Week, Washington, DC, May 19-24,

–  –  –


1. Ulrich, S., Wächtershäuser, A., Gaschott, T., Stein, J.

Die Butyrat-induzierte PPARγ-Expression ist nicht mit epithelialer Zelldifferenzierung assoziiert; Z Gastroenterol (2003) 41:764

58. Jahrestagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten, Nürnberg, September 17-20, 2003

2. Ulrich, S., Stein, J.

Die Butyrat-induzierte Steigerung der Spermin/SpermidinAcetyltransferase (SSAT) Aktivität wird über den Transkriptionsfaktor PPARγ vermittelt; Akt Ern Med (2004) 29(2) Nutrition 2004, Munich, May 6-8, 2004

3. Ulrich, S., Wächtershäuser, A., Loitsch, S., Gaschott, T., Stein, J.

Butyrate-induced PPARγ expression is not associated with epithelial cell differentiation; Gastroenterology 2004; 126 (4), Suppl.2 Digestive Disease Week, New Orleans, May 15-20, 2004

4. Ulrich, S., Huwiler, A., Wolter, F., Loitsch, S., Stein, J.

Resveratrol moduliert den Polyaminstoffwechsel kolorektaler Karzinomzellen über zwei unterschiedliche Signaltransduktionswege;

Z Gastroenterol 2004; 42(8):903

59. Jahrestagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten, Leipzig, September 1-4, 2004

–  –  –

polyphenols ZAFES Kick-off symposium “Lipid signaling”, Frankfurt/Main, October 14, 2004

7. Ulrich, S., Wächtershäuser, A., Caspary, W.F., Stein J.

Statins – from cardioprotection to colorectal cancer prevention ZAFES Kick-off symposium “Lipid signaling”, Frankfurt/Main, October 14, 2004

8. Ulrich, S., Wolter, F., Loitsch, S., Stein, J.

The phytoalexin resveratrol induces inhibition of ornithine decarboxylase via a ceramide signaling pathway 3rd International Symposium on PPARs, Monte Carlo, March 29-23, 2005

9. Daniel, C., Ulrich, S., Hagos, M., Loitsch, S., Stein, J.

Ursolic acid increases spermine/spermidine acetyltransferase activity in colorectal cancer cells via PPARγ signaling pathway 3rd International Symposium on PPARs, Monte Carlo, March 29-23, 2005

10. Ulrich, S., Wolter, F., Loitsch, S., Stein, J.

PPARγ fungiert als molekulares Target in der Resveratrol-vermittelten Modulation des Polyaminstoffwechsels Jahrestagung der Mitteldeutschen Gesellschaft für Gastroenterologie, Bad Nauheim, May 5-7, 2005

11. Ulrich, S., Hagos, M., Loitsch, S., Stein, J.

Pages:     | 1 |   ...   | 8 | 9 || 11 | 12 |   ...   | 16 |

Similar works:

«Hannover Medical University Clinic of Laryngology, Rhinology and Otology / University of Veterinary Medicine Hannover Investigation of Novel Auditory Implants of the Inferior Colliculus THESIS Submitted in partial fulfilment of the requirements for the degree DOCTOR OF PHILOSOPHY (Ph.D.) awarded by the University of Veterinary Medicine Hannover by Roger Calixto Lethbridge, Alberta, Canada Hannover 2011 Supervisor: Prof. Dr. Thomas Lenarz Professor and Chairman, Dept. of Otolaryngology, Medical...»

«Patient Epidemiology Factors of Unidentified Positive Reactivity in Solid-Phase and Test Tube PEG Antibody Detection Methods By Nichole M. Miller, BS SBB (ASCP)CM BloodCenter of Wisconsin 1 Abstract Background: Several publications have reported an increase in nonspecific reactions when automated technologies such as solid-phase are used for the detection of red blood cell antibodies. There is little known about the patient’s epidemiology factors surrounding nonspecific reactions and the...»

«STD Communications Database General Public Focus Group Findings Final Report Contract: 200-1999-00018, Task 24 Submitted to Division of Sexually Transmitted Disease Prevention National Center for HIV, STD, and TB Prevention Centers for Disease Control and Prevention By ORC Macro 3 Corporate Square, Suite 370 Atlanta, Georgia 30329 Phone: (404) 321-3211 Web: www.macroint.com February 2004 EXECUTIVE SUMMARY Introduction Sexually transmitted diseases (STDs) remain a significant public health...»

«RESEARCH REPORT ON THE COAL PILLAR RECOVERY UNDER DEEP COVER Office of Mine Safety and Health Research National Institute for Occupational Safety and Health Centers for Disease Control and Prevention Department of Health and Human Services February 2010 Table of Contents Page Executive Summary Background Purpose Approach to the Study on Coal Pillar Recovery Evaluation of the Conditions under Which Retreat Mining is Used Evaluation of Procedures and Technologies Used to Ensure Miner Safety...»

«GLAUCOMA NZ POSITION PAPER The Challenge of Glaucoma ‘The Challenge of Glaucoma’ outlines pathways to intervention in our community to prevent visual loss and blindness from glaucoma. This document, ‘The Challenge of Glaucoma’, outlines what can be done, what Glaucoma NZ has done, and most importantly what an intelligent individual could expect to be done if he passed through any of the pathways outlined. Refinements will be made but the broad pathways have been outlined pathways that...»

«TA POOLING: TOOLS AND LESSONS LEARNED A brief review of recent experiences Volker Hauck Heather Baser December 2005 DFID Health Resource Centre 5-23 Old Street London EC1V 9HL Tel: +44 (0) 207 251 9555 Fax: +44 (0) 207 251 9552 Title: TA POOLING: TOOLS AND LESSONS LEARNED: A brief review of recent experiences Authors: Volker Hauck and Heather Baser DFID Health Resource Centre 5-23 Old Street London EC1V 9HL Tel: +44 (0) 20 7251 9555 Fax: +44 (0) 20 7251 9552 TABLE OF CONTENTS Acknowledgements...»

«F ace pain A guide for patients and carers A Brain and Spine Disorders Booklet Face pain A guide for patients and carers Published by the Brain and Spine Foundation ©Brain and Spine Foundation 2002 Second edition ISBN 1 901893 16 2 First published by the Brain and Spine Foundation 1999 British Library of Cataloguing in Publication Data A catalogue record for this book is available from the British Library Editor, Brain and Spine Booklet Series: M Alexander CBiol MIBiol Medical illustrations:...»

«NEWBORN CARE BOOKLET Dr Supraja Chandrasekar & Dr Chetan Ginigeri About Us People Tree foundation is a unique, non profit organization started exclusively by young dynamic doctors belonging to various clinical specialties. This foundation aims to empower people by providing them with a wide range of evidence based medical topics to promote their health and prevent and treat medical problems in the family in partnership with their doctor. As most of our members are involved in emergency care and...»

«Guidance for Industry E2E Pharmacovigilance Planning U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER) April 2005 ICH Guidance for Industry E2E Pharmacovigilance Planning Additional copies are available from: Office of Training and Communication Division of Drug Information, HFD-240 Center for Drug Evaluation and Research Food and Drug Administration 5600 Fishers Lane...»

«European Chemicals Bureau European Union Institute for Health and Consumer Protection Risk Assessment Report European Chemicals Bureau CAS No: 79-10-7 EINECS No: 201-177-9 Existing Substances acrylic acid European Union Risk Assessment Report O OH acrylic acid C CH H2C CAS: 79-10-7 EC: 201-177-9 1st Priority List EUROPEAN COMMISSION JOINT RESEARCH CENTRE Volume: 28 EUR 19836 EN PL-1 European Union Risk Assessment Report ACRYLIC ACID CAS No: 79-10-7 EINECS No: 201-177-9 RISK ASSESSMENT LEGAL...»

«June 2010 A monthly sitrep. for the Rhodesian Services Association Incorporated Registered under the 2005 Charities Act in New Zealand number CC25203 Registered as an Incorporated Society in New Zealand number 2055431 PO Box 13003, Tauranga 3141, New Zealand. Web: www.rhodesianservices.org E-mail hbomford@clear.net.nz Phone +64 7 576 9500 Cell +64 27 545 8069 Fax +64 7 576 9501 Please Note that all previous publications are available on line at www.rhodesianservices.org/Newsletters.htm...»

«Fişa cu date de siguranţă SECȚIUNEA 1 IDENTIFICAREA SUBSTANŢEI/AMESTECULUI ŞI A SOCIETĂŢII/ÎNTREPRINDERII 1.1 Identificator de produs CAT® ELC (EXTENDED LIFE COOLANT) PREMIX 50/50 WITH EMBITTERMENT Numărul produsului: CPS226387 1.2 Utilizări relevante identificate ale substanţei sau amestecului şi utilizări contraindicate Utilizări Identificate: Antigel/Agent frigorific 1.3 Detalii despre furnizorul fişei tehnice de securitate Chevron Energy Technology Company Toxicology and...»

<<  HOME   |    CONTACTS
2016 www.dissertation.xlibx.info - Dissertations, online materials

Materials of this site are available for review, all rights belong to their respective owners.
If you do not agree with the fact that your material is placed on this site, please, email us, we will within 1-2 business days delete him.