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«Anastasia Ivanova, Ph.D. 1 4/1/2014 Anastasia Ivanova Department of Biostatistics University of North Carolina at Chapel Hill 3103-C ...»

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Liu, K., Ivanova, A., Snyder, E., Snavely, D. Entsuah, R. Case Study: An Adaptive Design that Uses a Utility Function to Identify the Best Dose in a Crossover Setting. ASA Biopharmaceutical /FDA Industry Workshop, Washington DC, September 2009.

Ivanova, A. Adaptive dose finding in non-life threatening diseases. JSM. Washington DC, August 2009.

Ivanova, A. Design and estimation in dose-ranging studies6-th St Petersburg Workshop on Simulation, St. Petersburg, Russia, July 2009.

Ivanova, A. Adaptive dose finding. The second International Workshop in Sequential Methodologies, Troyes, France, June 2009.

Ivanova, A. Finding the dose with the best efficacy/tolerability profile. ENAR. San Antonio, TX, March 2009.

Ivanova, A. An Adaptive Design for Identifying the Dose with the Best Efficacy/Tolerability Profile. Department of Statistics, George Masson University. Fairfax, VA, February 2009.

Ivanova, A. Dose-finding adaptive trials. Society of Clinical Trials annual meeting. St. Louis, May 2008.

Liu, K., Ivanova, A., Snyder, E., Snavely, D. A Three-Period Crossover Adaptive Dose Design.

Third Annual Adaptive Designs for Clinical Development. London, United Kingdom, May 2008.

Ivanova, A. Adaptive designs for dose-finding trials. Tutorial.. The 63rd annual Deming Conference on applied statistics. Atlantic City, December 2007.

Ivanova, A. Dose-finding for umbrella dose-response. Merck Research Laboratories.

Philadelphia, September 2007.

Ivanova, A. Dose-finding designs for Phase II A studies. GlaxoSmithKline Biostatistics Annual Conference. Philadelphia, September 2007.

Ivanova, A. Dose-finding based on t-statistic. Merck Research Laboratories. Rahway, September 2007.

Ivanova, A. Investigation of up-and-down strategies for isotonic dose-finding. MODA8, Spain, June 2007.

Ivanova, A. Adaptive designs for dose-selection trials. Merck Research Laboratories. Rahway, February 2007.

Ivanova, A. Dose-finding in oncology. GlaxoSmithKline. Cary, May 2007.

Ivanova, A. Adaptive dose selection trials. Adaptive Designs For Clinical Development Summit, Germany, March 2007.

Ivanova, A. Unified approach to treatment assignment in dose-finding trials CBI’s 1st Forum on Dose Finding Studies, Philadelphia, February 2007.

Ivanova, A. Non-parametric dose-finding designs: recent developments and examples.

GlaxoSmithKline Biostatistics Annual Conference. Cary, November 2006.

Anastasia Ivanova, Ph.D. 12 4/1/2014 Ivanova, A., Qaqish, B., and Schell, M. Continuous toxicity monitoring in phase I trials in oncology. Georgetown University, Washington DC, March 2006.

Ivanova, A. Aspects of teaching Biostatistics. How to teach Epidemiology, Prevention and Biostatistics in an MPH program, Saint Petersburg State University, Saint Petersburg, Russia, May 2005.

Ivanova, A. Dose-finding in life-threatening diseases: non-parametric methods. Designing and analyzing dose response clinical trials, Philadelphia, PA, November 2004.

Ivanova, A. Analysis of primary and secondary outcomes in trials allowing stopping based on secondary outcomes. Understanding applying and not misusing statistical techniques, Gaithersburg, MD, October 2004.

Ivanova, A., Qaqish, B., and Schell, M. Continuous toxicity monitoring in phase II trials in oncology. UMBC, Baltimore, MD, October 2004.

Ivanova, A. Response-adaptive designs: ethics and efficiency of estimation. Workshop on Adaptive designs, Fields Institute, Toronto, September 2003.

Berger, V., Zhou, J., Ivanova, A., and Tremmel, L. Exact adjustment for ordinal covariates in randomized trials using partial orderings. ENAR, Tampa, FL, March 2003.

Coad, S., and Ivanova, A. Sequential adaptive urn designs with elimination for comparing several treatments. Meeting on Response Adaptive Clinical Trials, Sandwich, UK, November 2002.

Rosenberger W.F., Stallard, N., and Ivanova, A. Optimal adaptive designs for binary response trials. Department of Biostatistics, UCLA, January 2002.

Rosenberger W.F., Stallard, N., and Ivanova, A. Optimal adaptive designs for binary response trials. Department of Statistics, University of California, Santa Barbara, February 2002.

Barrier, R. and Ivanova, A. Selection bias in adaptive clinical trials. Joint Statistical Meeting, Atlanta, GA, August 2001.

Berger, V. and Ivanova, A. An alternative to the complete randomized block procedure. Joint Statistical Meeting, Atlanta, GA, August 2001.

Ivanova, A. Designing an epidemiologic study. HIV and AIDS Epidemiology Meeting. St.

Petersburg, May 2001.

Rosenberger W.F., Stallard, N., and Ivanova, A. Optimal adaptive designs for binary response trials. SmithKline Beecham, Philadelphia, PA March 2001.

Rosenberger W.F., Stallard, N., and Ivanova, A. Optimal adaptive designs for binary response trials. Department of Statistics, University of South Carolina, November 2001.

Rosenberger W.F., Stallard, N., and Ivanova, A. Optimal adaptive designs for binary response trials. The EMMES Corporation, Rockville, MD, November 2001.

Ivanova, A. Drop-the-loser rule in medical trials. University of Maryland, Baltimore, MD, October 2000.

Ivanova, A. and Berger, V.W. Adaptive tests for ordinal categorical data. NCI, Bethesda, MD, October 2000.

Ivanova, A. Drop-the-loser rule in medical trials. University of Georgia, Athens, GA, March 2000.





Ivanova, A. Drop-the-loser rule in medical trials. Columbia University, New York, NY, February 2000.

Anastasia Ivanova, Ph.D. 13 4/1/2014 Rosenberger W.F., Stallard, N., and Ivanova, A. Optimal adaptive designs for binary response trials. PhRMA/FDA Workshop, Washington DC, October 2000.

Ivanova, A. Drop-the-loser rule in medical trials. UNC at Chapel Hill, Chapel Hill, NC, October 1999.

Ivanova, A. and Berger, V.W. Adaptive tests for ordinal data. The 1999 CCF-CWRU-OSU Statistics Symposium, Cleveland, OH, May 1999.

Berger, V.W. and Ivanova, A. The conditional t-test of stochastic order is biased and least stringent for the product multinomial distribution. International Chinese Statistical Association (ICSA) Meeting, New Brunswick, NJ, May 1997.

Other Presentations (prior to 2006) Coad, S., and Ivanova, A. The use of triangular test with response-adaptive treatment allocation.

55th Session of the International Statistical Institute, Sydney, Australia, April 2005.

Wang, K., and Ivanova, A. Bayesian designs for two-dimensional phase I trials. JSM, San Francisco, CA, August 2003.

Ivanova, A. New approach to dose-finding studies. Infectious Diseases Conference, UNC at Chapel Hill, July 2003 (invited as CFAR development grant recipient).

Wang, K., and Ivanova, A. Designs for phase I trials with two agents. ENAR, Tampa, FL, March 2003.

Berger, V. and Ivanova, A. Enhancing allocation concealment through less restrictive Randomization Procedures. ENAR, Charlotte, NC, March 2001.

Ivanova A. and Berger V.W. Adaptive tests for ordinal categorical data. Joint Statistical Meeting, Baltimore, MD, August 1999.

Melki S.A., Safar, A., Martin J., Ivanova A. and Adi, M. Potential acuity pinhole: A simple method to measure potential visual acuity in patients with cataracts, comparison to PAM.

Meeting of the American Academy of Ophthalmology, New Orleans, November 1998.

Ivanova A. and Durham, S. A birth and death urn for randomized clinical trials. Joint Statistical Meeting, Dallas, TX, August 1998.

Ivanova A. A birth and death urn for randomized clinical trials. St. Petersburg Workshop on Simulation, St. Petersburg, Russia, June 1998.

Ivanova A. and Rosenberger W.F. A birth and death urn for randomized clinical trials.

Mid-Atlantic Probability and Statistics Day, Baltimore, MD, October 1997.

Ivanova A.V. and Rosenberger W.F. A birth and death urn for randomized clinical trials.

Graduate Student Research Day, Baltimore, MD, April 1997.

Ivanova A. Stability of algorithms when solving partial differential equations with the Monte Carlo method, Mid-Atlantic Probability and Statistics Day, Baltimore, MD, October 1996.

Teaching

–  –  –

Probability and Statistical Inference I Fall 2000, 2002, 2003, 2004, 2005, 2011, Nonparametric Statistics (Case Western Reserve) Spring 1999

–  –  –

Service UNC Academic Committees Task Force on Scientific Review of IRB Applications, 2013 – present Advisory Committee for Diversity Programs and Recruitment, school-wide committee, 2012 – present BSURE program committee (chair) 2008 – present Social committee 2008 – present Examination committee, 2000 – present Protocol Review Committee, Lineberger Cancer Center, University of North Carolina at Chapel Hill, 1999 – present Search committee, Department of Biostatistics, 2001, 2011 Search committee, Lineberger Cancer Center, 2004, 2006, 2007, 2008, 2009, 2011, 2012.

New MPH program at St. Petersburg State University, Russia (Fogarty), 2004 – 2005.

Stochastic Processes Course Committee, Department of Statistics and the Department of Biostatistics, 1999 Data and Safety Monitoring Board Service Member, Data and Safety Monitoring Committee, Lineberger Cancer Center, University of North Carolina at Chapel Hill, 1999 – present Member, Hematology Data and Safety Monitoring Board, National Institutes of Health, National Heart Lung and Blood Institute, 2007 – present Member, Data and Safety Monitoring Committee, Applied Genetic Technologies Corporation, 2008 – present Member, Data and Safety Monitoring Board, Ikaria Pharmaceuticals, 2009 – 2013 Member, Data and Safety Monitoring Board, PhotoThera, 2010 – 2012 Member, Data and Safety Monitoring Board, Salix, 2011 – present Editorial Service Associate Editor, Statistics in Medicine, 2006 – present Associate Editor, Biometrics, July 1, 2011 – December 31, 2013 Guest Associate Editor for the special Gary Koch Festschrift Issue for Statistics in Biopharmaceutical Research, 2011 Other Service Steering committee for 2014 FDA/Industry Statistics Workshop The academic advisor to Oncology subgroup under the Drug Information Association (DIA) Adaptive Designs Scientific Working Group, 2013 - present The academic advisor to Cytel’s Dose Finding Consortium, 2012 - present Ad Hoc Reviewer (selected list) Annals of Statistics; Biometrika; Biometrics; Biostatistics; Journal of the Royal Statistical Society B; Journal of the American Statistical Association; Journal of Biopharmaceutical Statistics; Journal of Clinical Oncology; Journal

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